Polyprenyl Immunostimulant™
Helping the body fight diseases®
Available worldwide*
Polyprenyl Immunostimulant™ (PI) is the only USDA-approved therapeutic for the treatment of Feline Viral Rhinotracheitis (FVR).
What is Polyprenyl Immunostimulant™?
Polyprenyl Immunostimulant™ is manufactured by Sass & Sass, Inc. and is the only therapeutic approved by the USDA for the treatment of feline rhinotracheitis. It reduces the severity of the disease in cats. It is a very safe, well-tolerated oral liquid designed with cats in mind. Polyprenyl Immunostimulant™ is formulated as a 2 mg/mL solution of phosphorylated polyprenols and is offered in 10 mL vials or packs of 6 x 10 mL vials.
Polyprenyl Immunostimulant™ works by upregulating innate immunity and directing cellular immune response. It is a very safe product which aids in the reduction of clinical signs resulting from rhinotracheitis infection in cats 8 weeks of age or older. Polyprenyl Immunostimulant™ is often referred to as PI or PPI.
Polyprenyl Immunostimulant™ quick facts
Polyprenyl Immunostimulant™ reprograms the cat's innate immunity, restores quality of life, returning your cat to a healthy and happy self.
Polyprenyl Immunostimulant™ reduces the severity of clinical signs resulting from feline herpesvirus infection (URI, FHV-1, FVR, FRV) in cats eight weeks of age or older.
Polyprenyl Immunostimulant™ is administered orally; a single dose equals 0.25 ml/kg. The recommended dosage is two oral doses of Polyprenyl Immunostimulant™ daily for 15 days.
Safety studies in 390 cats showed that oral administration of 0.5 mg/kg of Polyprenyl Immunostimulant™ twice daily for 15 days is safe for cats eight weeks of age or older. No signs of illness were note in toxicity tests conducted at 5 mg/kg dose of Polyprenyl Immunostimulant™.
Polyprenyl Immunostimulant™ is the only USDA-approved oral treatment for feline rhinotracheitis. No analogs or similars exist.
• 100% sourced and manufactured in the USA.
• Exceptional safety record: no adverse events reported during studies or seven years post-market introduction.
• Small volume of liquid is easy to administer to cats.
Polyprenyl Immunostimulant™ Research
Feline Viral Rhinotracheitis and URI Research, Trials, and USDA Regulations.
Veterinarians and customers often ask questions about Polyprenyl Immunostimulant™ trials. Our past, current, and planned Sass & Sass, Inc. clinical studies and trials that involve Polyprenyl Immunostimulant™ (PI, PPI) are listed here.
Feline Infectious Peritonitis (FIP) Research, Trials, and USDA Regulations.
Veterinarians and researchers also study and experiment with Polyprenyl Immunostimulant™ in other infections and other species. You may read about FIP research here.
Published Research
Legendre AM, et al. Front Vet Sci, February 14, 2017
Legendre AM, Bartges JW. 2009 JFMS, 11, 624-626
Legendre AM, et al. Front Vet Sci February 27. 2017
* Polyprenyl Immunostimulant™ is not or may not be available in a small number of countries due to country-specific regulations or contractual limitations.
